Postoperative complications in children with Crohn’s disease: an analysis of risk predictors

BACKGROUND: Crohns disease is an incurable progressive condition of the gastrointestinal tract in which up to 90% patients undergo one or more surgical interventions during their lifetime. Despite active development and implementation new techniques for treatment disease, incidence postoperative complications remains high, i.e., 25%30%. Until now, influence various factors on outcomes choice differentiated children with remain highly debatable.
 AIMS: To study identify possible risk adolescents disease.
 MATERIALS AND METHODS: A retrospective nonrandomized clinical included 164 pediatric (boys, n = 106, 65%) complicated forms disease. Early results intestines were analyzed (up 30 days after surgery). Postoperative noted 15% cases initial surgery (20/133). In half (66/133) re-interventions performed at different times surgery, detected 14% (9/66). determine dichotomous variables, contingency tables constructed calculation odds ratio (OR) 95% confidence interval (95% CI). Differences recognized as statistically significant p 0.05.
 RESULTS: The following predictors identified: penetrating strictures (OR 5,1; CI 1,7314,8; 0,0047), intestinal fistulas 5; р fibrosis mucosal biopsy 8,9; 1,2253; 0,0093), steroid therapy before 14,6; 1,08135; 0,0105), onset CD 6 years age 10,8; 1,16137; 0,0177), combination any localization lesions upper 13,8; 1,01143; 0,0247), severe hypoalbuminemia 9,62; 1,04122; 0,0228) no specific 0,0177).
 CONCLUSIONS: strategy preoperative period based identification reliable adverse helps reduce complications. This improves early